Aqua Teen Hunger Force - Season 1 Episode 14

When Meatwad learns through observation that he has no brain, his attitude changes; he becomes listless, bitter, and despairing. Frylock, hoping to cheer Meatwad up, searches for the means to acquire a brain. Carl obliges – with a fresh human brain obtained care of his friend, Terry. The effects of the brain transplant are quite dramatic on Meatwad; he begins to read more frequently, he enlarges considerably, and he even goes so far as to create an "anti-matter eliminator."